Medicinal Chemistry, Drug Discovery & Drug Delivery

ChemMedChem-Antimicrobials and Infectious Agents

Microbes produce a wide range of molecules that can modulate eukaryotic immune responses. These agents interfere with the growth and reproduction of causative organisms like bacteria, fungi, parasites, virus etc. The journal of antimicrobial agents stocks up information about antibacterial, antifungal, antiviral, anti protozoal, anti-algal agents and their methods of detection, different therapies and advanced treatments to overcome diseases. These include factors that subvert protective mechanisms in order to facilitate pathogen colonization and persistence. Viral, bacterial and parasite-derived molecules have been identified that can inhibit inflammatory responses.  The indiscriminate use of conventional antibiotics has generated high rates of microbial resistance. Antimicrobial peptides (amps) constitute a promising alternative as therapeutic agents against various pathogenic microbes. These therapeutic agents can be isolated from different organisms, being widespread in nature and synthesized by microorganisms, plants and animals (both invertebrates and vertebrates).