Chemical Biology

Chemical biology is the study of the chemicals and chemical reactions involved in biological processes, incorporating the disciplines of bioorganic chemistry, biochemistry, cell biology and pharmacology. Chemicals – including natural small molecules, such as lipids, carbohydrates and metals, or non-natural probe or drug molecules – are used to gain insight into biological problems at a mechanistic level. There are some biological problems demand molecular and quantitative answers that can only be supplied by tools and approaches derived from chemistry — such as single-molecule measurements, single-cell imaging, and the use of exogenous molecules to modulate the activity of cellular components. While yeast metabolic engineering has focused on assembling pathways in the cell cytosol, there is growing interest in embracing subcellular compartmentalization. Beyond harnessing distinct organelle properties, physical separation of organelles from the cytosol has the potential to eliminate metabolic crosstalk and enhance compartmentalized pathway efficiency.



In Current Opinion in Chemical Biology, we help the reader by providing in a systematic manner:

1. The views of experts on current advances in chemical biology in a clear and readable form.

2. Evaluations of the most interesting papers, annotated by experts, from the great wealth of original publications.

  • Potential use of stem cells for regeneration
  • Harnessing yeast organelles for metabolic engineering
  • Si-RNA a tool in chemical biology
  • Discovery of biomolecules through metagenomics
  • Protomics

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Chemical Biology Conference Speakers

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