Chem-Virology (Zika Virus)

Zika virus (zikv) is an arbovirus belonging to the flaviviridae family. Vector-mediated transmission of zikv is initiated when a blood-feeding female aedes mosquito injects the virus into the skin of its mammalian host, followed by infection of permissive cells via specific receptors. Zikv contains a positive, single-stranded genomic RNA encoding a polyprotein that is processed into three structural proteins, i.e., the capsid (c), the precursor of membrane (prm), and the envelope (e), and seven nonstructural proteins, i.e., ns1 to ns5. Most individuals infected with zika virus experience mild or no symptoms. about 25% of infected people develop symptoms 2-10 days after infection, including rash, fever, joint pain, red eyes, and headache. There are currently no antiviral drugs or vaccines that can be used to treat or prevent infection with zika virus. We do have a safe and effective vaccine against another flavivirus, yellow fever virus. Mosquito control is the only option for restricting zika virus infection. Measures such as wearing clothes that cover much of the body, sleeping under a bed net, and making sure that breeding sites for mosquitoes (standing water in pots and used tires) are eliminated are examples.

 

  • Rapid Transmission
  • ZIKV-Processing on the microfluidic cassette
  • ZIKA virus infection may prevent reinfection
  • Zika infection-A global threat to human population
  • Major possible symptoms
  • Drugs and vaccines available so far

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Chem-Virology (Zika Virus) Conference Speakers

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