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14th World Congress on Medicinal Chemistry and Drug Design

Edinburgh, Scotland

Alex R Khomutov


Alex R Khomutov

Russian Academy of Sciences, Russia

Biography

Alex R.Khomutov principle investigator, Engelhardt Institute of Molecular Biology, Moscow, Russia. He graduated Chemical Faculty of Moscow State University in 1976. He got PhD and later D.Sc. degrees in Bioorganic Chemistry in Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow. The main field of the interests are design and synthesis of the inhibitors/unnatural substrates of the enzymes of amino acids metabolism, including those related to biosynthesis and catabolism of biogenic polyamines spermine and spermidine, and investigation of the interaction of these analogues with enzymes and activity in cell cultures. In 2017 he was a chair of Polyamines Gordon Research Conference. A.R.Khomutov is a co-author of more than 120 papers in per-reviewed Journals.

 

Abstract

Abstract : Isomers and diastereomers of C-methylated spermidine and spermine: Synthesis and biochemical application