Université du Québec à Trois-Rivières Canada
Institute of Perm State University Russia
Barcelona Supercomputing Center Spain
P.G. Demidov Yaroslavl State University Russia
Unversité de Paris-Saclay France
University of Massachusetts Dartmouth USA
Novartis Institute of Biomedical Research USA
University of Nebraska Medical Center USA
Recommended Global Chemistry Conferences
Medicinal Chemistry 2019
Chemistry Conferences welcome chemical professionals, researchers, professors, scientific communities, delegates, students, business professionals and executives from all over the world to attend the “11th World Congress on Medicinal Chemistry and Drug Design” which is to be held during June 10-11, 2019 at Edinburgh, Scotland which includes prompt Keynote presentations, Oral talks, Poster presentations and Exhibitions.
Medicinal Chemistry 2019 which is the primordial chemistry conferences serves as a global platform to discuss and learn about Medicinal Chemistry, Pharmaceutical Sciences, Drug Design and Drug Development, CADD (Computer Aided Drug Design), Bioorganic and Medicinal Chemistry, Pharmacology and toxicology, Anticancer agents in Medicinal Chemistry, Analytical Chemistry, Pharmaceutical Industry, Organic Chemistry, Clinical Pharmacology, Evolution of Organic and Medicinal Chemistry in Pharma, Organic and Medicinal Chemistry Technologies for Drug Discovery, QSAR (Quantitative Structure-Activity Relationship) Fragment-Based Drug Design, Applications of Organic and Medicinal Chemistry in Drug Discovery, Market Dynamics, Conclusions and Future Trends, Medicinal Plants
In the light of this theme, the conference series aims to provide a forum for international researchers from various areas of chemistry, pharmacy, Medicinal Chemistry and Drug Design by providing a platform for critical analysis of new designing, and to share latest cutting-edge research findings and results about all aspects of Medicinal Chemistry. The current meeting of chemistry conferences will be a multinational gathering and present major areas such as Medicinal Chemistry, Pharmaceutical Sciences, Drug Design and Drug Development, Organic Chemistry and overall applications.
Professors in Pharmaceutical sciences and Chemistry
Associate and Assistant Professors in Pharmaceutical sciences and Chemistry
Post-doctoral and Researchers in Pharmaceutical sciences and Chemistry
Heads of Pharmaceutical sciences and Chemistry Departments
Post Graduates and Graduates in Pharmaceutical sciences and Chemistry
Chemical Scientists working on Medicinal Chemistry
Experts in the development of Medicinal Chemistry
The field of Medicinal Chemistry and Chemistry involves wide range of sectors of markets growing respectively.
Conference Series organizes 1000+ Global events every year across the globe with support from 1000+ more scientific societies and Publishes 700 Open access journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
Over the last decade, industry’s productivity has been declining with rising R&D costs and time taken to reach market. Medicinal chemistry is defined as a focused science that is developed to cover a wide range of fields related with identification, synthesis and drug development for therapeutic applications. This science has evolved from medical chemists focusing on drug target or pathway in mind and league of elaborative chemistry-driven processes to modern generation of high-throughput screening (HTS) libraries that are created by combinatorial chemistry based on few structural distinctions across large drug like scaffolds.
This change was needed because of high attrition rate in pre-clinical and incubation drug development studies because of earlier methods. While the primary task of medicinal chemists has not changed significantly over a period of time, the computational tools and chemicals and perspectives at their clearance or removal have advanced extensively.
The various tools of medicinal chemistry are in silico modeling, structure-based drug design (SBDD), comparative molecular field analysis (CoMFA) or 3D QSAR method. In particular the fragment-based drug design promisingly stands out because of substantial improvements in research and productivity. One of the primary challenges of drug discovery is to design a robust drug that is both safe and effective in a wide range of population. The various drug designing types are structure-based drug design, natural products-based drug design, fragment-based drug design, diversity oriented synthesis and chemogenomics.
Medicinal Chemistry for Drug Discovery Market: Trends
Due to modern technology an alternative approach to the large combichem libraries (10,000 plus molecules) is available, these are smaller focused arrays known as chemogenetic arrays that assists for confining of particular pharmacophore model for specific family to target but considering ADME and drug-like properties. The compound arrays must be synthetically feasible and to minimize the attrition rate in preclinical testing, must also consist of specific properties regarding adsorption, distribution, metabolism, elimination and toxicity (ADMET).
During this process the ADMET constraints established from information mining, in vitro and in vivo studies are often compiled into computational packages to enable chemists to predict the drug-likeliness of a compound.
The recent market trends observed with medicinal chemistry operations are outsourced by most of the pharmaceutical companies because this helps the companies to pace up the research process making it time and cost efficient. The outsourcing trend observed from the North American and European pharmaceutical companies to the companies of developing companies like India, China and Others from Asian continent.
Medicinal Chemistry for Drug Discovery Market: Opportunities and Competitive Dynamics
The mightiest challenge in this industry is to reduce the number of drugs that fail in pre-clinical stages, as this facilitates the manufacturer to enter the market with a high priced drug. But since the ADME profiling used in silico and cellular approaches have successfully reduced the attrition rate. According to industry experts currently structure-based drug design has high acceptance followed by fragment-based variation, natural products, while diversity oriented synthesis and chemogenomics have negligible market shares. The top five active therapeutic research areas are cancer, infections, neurological, gastrointestinal, endocrine and cardiovascular.
Drug discovery is expected to be largely practiced at small niche biopharmaceutical companies around the world in the U.K., U.S., Western Europe, Eastern Europe, China, India, Brazil, South Africa and Mexico as investments, time and risks are comparatively less in this operations model than the traditional. Overall the medicinal chemistry has improved all these years with all updated technologies and methodologies.
The importance of small and medium scaled companies will increase in this market as it will reduce the time and cost for a big pharmaceutical company. Hence, in drug discovery medicinal chemistry plays important role but still the accuracy and precision of the study needs to be improved to achieve minimum rejections in the preclinical studies.
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Pharmaceutical market in Edinburgh City