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Dorra Abdelmalek Driss

University of Sfax, Tunisia

Biography

Dorra Abdelmalek Driss is currently working as an assistant Researcher at Centre of Biotechnology of Sfax CBS-Sfax, University of Sfax. She does research in Engineering, Biochemistry Computer Science and Signaling pathways science. Hers current projects are Targeting EGFR family kinases: development of new molecules: design, synthesis and in vitro assays and Generating Active Human Kinases (ERBB family) Using Pichia Pastoris As A Host For Functional Assays And For Drug Discovery Purposes Investigating Possible Inhibitors That Can Be Used As Anticancer Agents.

Abstract

Abstract : Density functional theory and molecular dynamics simulation support newly designed reversible tyrosine kinase inhibitors targeting double mutant Epidermal Growth Factor Receptor (EGFR)