14th World Congress on Medicinal Chemistry and Drug Design
Karol S. Bruzik
University of Illinois, USA
Karol Bruzik received his BSc. degree (1972) from the Technical University of Lodz, Poland, and his PhD. (1980) and DSc. (1987) degrees from Polish Academy of Sciences. After postdoctoral work at The Ohio State University (1981-83 and 1990-93), he joined the Department of Medicinal Chemistry and Pharmacognosy at the University of Illinois at Chicago as Assistant Professor, and is now Professor and Associate Head. He is an author of more than 100 peer review publications in the area of organic and bioorganic chemistry, enzyme mechanisms, phosphoinositide signaling and allosteric modulators of ligand-gated ion channels, with emphasis on GABA-A receptors.
Abstract : Approach to GABA-A receptor isoform-selective allosteric agonists