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Zhongli Gao


Zhongli Gao

Sanofi, USA

Biography

Zhongli Gao is currently a Senior Principal Scientist at Sanofi. He received his PhD in Organic Chemistry from the City University of New York in 1993. Upon graduation, he carried out his Post-doctoral Research on the total synthesis of spinosyn-A supervised by Professor Paquette at Ohio State University. He joined Hoechst Pharmaceuticals, one of the predecessor companies of Sanofi in 1995. He has worked on a broad range of disease areas in CNS, respiratory, inflammation, oncology, and rare disease involving GPCRs, proteases, enzymes, kinases, ion channels and transporters. He has led many projects in advancing compounds into clinical and preclinical decisions.

Abstract

Abstract : Drug design via a scaffold hopping strategy: Case studies on discovery of clinical candidates H3 receptor antagonist and β-tryptase inhibitor