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Abdulmajeed S H AlSamarrai

Abdulmajeed S H AlSamarrai

Department of Chemistry, University of Samarra, Iraq

Title: Synthesis and characterization of 2-((4R,4aR,5aS,6S)-1,3-dioxo3m3a,4,4a,5,5a6,6a-octahydro-4,6- ethenocyclopropa[f]isoindol-2(1H)-yl)-N-(substituted phenyl) acetamides anticipated to have HIV- 1 activity

Biography

Biography: Abdulmajeed S H AlSamarrai

Abstract

This work includes the synthesis of some new 2-((4R,4aR,5aS,6S)1,3-dioxo3,3a,4,4a,5,5a6,6a-octahydro-4,6-ethenocyclopropa[f]isoindol-2(1H)yl)-N-(substituted phenyl) acetamides (3-11) by reaction of (4R,4aR,5aS,6S)-1,3-dioxo3,3a,4,4a,5,5a,6,6aoctahydro4,6ethenocyclopropa[f]isoindole1,3(2H,3aH)-dione (1) with 2-chloro-N-(substituted phenyl) acetamides (2) in the presences of potassium carbonate in refluxing acetonitrile as a solvent. These compounds have been identified by spectroscopic methods including, IR, 1H-NMR, 13C-NMR and elemental analysis (CHN).