Abdulmajeed S. H. AlSamarrai
University of Samarra,
Title: Synthesis and Characterization of 2-((4R,4aR,5aS,6S)-1,3-dioxo3m3a,4,4a,5,5a6,6a-octahydro-4,6-ethenocyclopropa[f]isoindol-2(1H)-yl)-N-(substituted phenyl) acetamides anticepted to have HIV-1 activity
Biography
Biography: Abdulmajeed S. H. AlSamarrai
Abstract
This work includes the synthesis of some new 2-((4R,4aR,5aS,6S)-1,3-dioxo3,3a,4,4a,5,5a6,6a-octahydro-4,6-ethenocyclopropa[f]isoindol-2(1H)-yl)-N-(substituted phenyl) acetamides (3-11) by reaction of- (4R,4aR,5aS,6S)-1,3-dioxo3,3a,4,4a,5,5a6,6a-octahydro-4,6-ethenocyclopropa[f]isoindole1,3-(2H,3aH)-dione (1) with 2-chloro-N-(substituted phenyl) acetamides (2) in the presences of potassium carbonate in refluxing acetonitrile as a solvent.These compounds have been identified by spectroscopic Methods including, IR, 1H-NMR,13-NMR and elemental analysis (CHN).
