Mitsuji Yamashita
Shizuoka University, Japan
Title: Preclinical researches on novel sugar dendritic Gd-DTPA MRI contrast agents and IER5/Cdc25B targeted phospha sugar antitumor agents to innovate in cancer therapy
Biography
Biography: Mitsuji Yamashita
Abstract
Innovative and strategic materials against tumor cells to decrease sharply the number of dead people by tumors are desired eagerly. To innovate in medical technologies of diagnosis and cure for various kinds of tumors by novel medicinal materials, i.e., sugar dendritic Gd-DTPA complex MRI contrast agent (DEN-OH) and IER5/Cdc25B targeted novel phospha sugar antitumor agents (TBMPP) were prepared and evaluated in vitro and in vivo methods, and then these novel medicinal materials were revealed preclinically to have excellent characters against tumor cells.