Medicinal Chemistry, Drug Discovery & Drug Delivery

Hematology/Oncology and Stem Cell Therapy

Targeting modulation of T-cell co-stimulation is one approach that aims to fight the cancer rather than targeting the tumor to eradicate the disease. This approach may enhance cells’ antitumor activity and potentially leads to a response that can last

• Cancer immunotherapy is a rapidly emerging field supported by compelling single-agent data, and more recently, with very encouraging combination data
• Immunotherapeutic approaches may provide improved, durable antitumor activity by amplifying and self-renewing immune response and utilizing long-term memory
• Preclinical and early clinical studies indicate a potential to improve efficacy using combination approaches involving immunotherapeutic agents with differing modes of action
• Immunotherapeutic agents could form the backbone of numerous potential combinations and indications in various lines of therapy