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Abdulmajeed S H AlSamarrai

Abdulmajeed S H AlSamarrai

Department of Chemistry, University of Samarra, Iraq

Title: Synthesis and characterization of 2-((4R,4aR,5aS,6S)-1,3-dioxo3m3a,4,4a,5,5a6,6a-octahydro-4,6- ethenocyclopropa[f]isoindol-2(1H)-yl)-N-(substituted phenyl) acetamides anticipated to have HIV- 1 activity

Biography

Abdulmajeed S H AlSamarrai was awarded a BSc in chemistry by the Mosul University of Iraq and MSc in analytical chemistry , by Baghdad University of Iraq and was awarded a PhD in organic chemistry by university of Birmingham/ UK in 1984. He is an assistant professor, department of chemistry, Tikrit university , Iraq (1991-2001). Then since 2001, he is a faculty member in the department of chemistry at the University of Samarra, Iraq and he is working as a professor of organic chemistry. Dr. ALSamarrai research interests are on organic synthesis of heterocyclic compounds and has published about 30 papers in reputed journals.

Abstract

This work includes the synthesis of some new 2-((4R,4aR,5aS,6S)1,3-dioxo3,3a,4,4a,5,5a6,6a-octahydro-4,6-ethenocyclopropa[f]isoindol-2(1H)yl)-N-(substituted phenyl) acetamides (3-11) by reaction of (4R,4aR,5aS,6S)-1,3-dioxo3,3a,4,4a,5,5a,6,6aoctahydro4,6ethenocyclopropa[f]isoindole1,3(2H,3aH)-dione (1) with 2-chloro-N-(substituted phenyl) acetamides (2) in the presences of potassium carbonate in refluxing acetonitrile as a solvent. These compounds have been identified by spectroscopic methods including, IR, 1H-NMR, 13C-NMR and elemental analysis (CHN).